SALIENT
Project Salient is an effort to federate government data for unified, real-time biodefense.
AI agents can do real work in biodefense
Fuse multimodal signal into one operational picture
Biothreat operations run on many kinds of data and involve complex coordination. Give each team the view it needs, drawn from one fast, coherent picture, so they can escalate early and respond before a threat spreads.
Fusion has to happen across institutional and geographic boundaries, not only between modalities
And moving data between sites or institutions is often impossible
Our environment enables shared standards between deployments, allowing automated analysis across difficult boundaries
Labs, sites, and field teams each hold part of the picture. Shared data standards let them connect and coordinate in real time, while each keeps control of its own data. When a threat emerges, they can start working it together immediately, without ad hoc data transfers.
Ask any question of every site, the moment a threat appears
Centralize it all before you can ask.
Decide what matters before you look.
Ask anything, the moment it matters.
Most analysis tools use incompatible standards, so chaining them together is slow, manual work
React faster with a comprehensive tool environment
Move from biosurveillance to threat characterization to countermeasures on the same datasets, with results from each phase ready to use in the next.
- Metagenomic classification
- Host depletion
- Read alignment
- Variant calling
- Lineage assignment
- Resistance genes
- Genome assembly
- Phylogenetics
- Engineering detection
- Virulence factors
- Structure prediction
- Epitope prediction
- Antibody design
- Assay design
- Binding prediction
Pick the right scale for the job
The full tool environment packaged into an appliance at any scale, from a laptop to petabyte rack-scale deployments.

Haul less data, and run on any machine
Biological data artifacts can be large, and moving them is slow and brittle. Our environment is built around fast, chunked file formats, so moving and processing data is efficient.
Data is indexed efficiently where it lives, so a search runs at the site and returns only what matches.
Our formats are chunked by design, so what does move goes in small pieces.
The same tools run on a low-memory machine or across a large HPC cluster in distributed mode.
Biodefense is a hard problem, and it should not fail for mundane reasons
Limited data visibility, incompatible tools, and sovereignty constraints hinder decisions. HoX is a connected environment designed to fix all three.
REQUEST A BRIEFING